The coming week in General Hospital (Sept. 22-26, 2025) promises to be emotionally rich, heavy with heartache, and full of moments that will test the strength and loyalty of Port Charles’ residents.

Monica Quartermaine’s death isn’t just a turning point—it’s the backdrop for a series of revelations, reckonings, and perhaps even forgiveness.

Monday, Sept. 22 — Bad News and Tumultuous Emotions

The week begins with several characters receiving unsettling news.

Carly and Sonny both get hit with unpleasant developments—ones that may tie back to Monica’s passing or ongoing investigations in the wake of recent chaos. Anna Devane is caught off guard at General Hospital, perhaps by new information or a confession she didn’t expect. Britt, already emotionally fragile, is set to be shaken to her core by something looming in her world. Molly, finally feeling the weight of what she’s held inside, shares something with Alexis—could it be about Cody? About regret, fear, or guilt? Meanwhile, Cody will find himself unable to trust Brook Lynn after past betrayals—today’s spoilers tease that Brook Lynn may finally overstep in a way he can’t overlook.

Midweek — Grief, Guilt, and Search for Solace

By Tuesday and Wednesday, Port Charles’ grief deepens. Lulu turns to Tracy for guidance or comfort—Tracy being one who embodies both strength and sorrow in the wake of Monica’s death. Britt deals with bouts of guilt that hint she’s carrying something heavier than grief; something she may have contributed to or failed to stop. Meanwhile, Martin takes a mysterious call that may introduce yet another complicating layer to the Quartermaine legacy. Felicia and Anna reconnect, perhaps to process loss or compare notes about what Monica meant, and Portia spends time with Isaiah—either to support him or look for emotional grounding.

Thursday, Sept. 25 — The Funeral

The big moment arrives: the Quartermaines and all of Port Charles gather to say farewell. Monica’s funeral anchors the week. Expect heartfelt eulogies, tears, and perhaps even some unexpected visitors. Characters who have been distant may show up, grudges may boil to the surface, and suppressed emotions might burst forth. Given Monica’s role as matriarch, many will be forced to reckon with how her death changes the power dynamics within the family—and who steps up, who steps back.

Friday, Sept. 26 — Legacy & Aftershocks

Following the funeral, the impact begins to ripple. Port Charles isn’t going to simply mourn and move on; the aftermath of Monica’s life and death will influence how characters see their own futures. There’s word of a soap legend showing up—someone whose arrival at the funeral could shake things up, either by revealing secrets, bringing closure, or stirring tension.

Relationships will be tested—old wounds reopened, some bonds strengthened, others possibly broken. People might reflect on what Monica taught them, what she missed, and how to carry the family forward without her guiding presence.

Why This Week Matters

Monica Quartermaine was more than a grandmother, more than a doctor—she was a symbolic anchor for Port Charles’ moral center. This week’s episodes take that anchor and examine the void it leaves. As grief, guilt, loyalty, and regret all come to the surface, viewers will see who is defined by Monica’s legacy—and who struggles without it. Her absence changes everything: the responsibilities people feel, the conversations they’ve avoided, and the truths they can’t hide any longer.

For real General Hospital fans, these next few episodes are a emotional gauntlet—one that reminds us that in this town, love and loss are never far apart, and legacy isn’t just what you leave behind, but what you choose to carry forward.