Port Charles is poised for a whirlwind autumn on General Hospital, with emotional farewells, comeback specters, and a baking-cast of new faces that promise high-stakes drama around every corner.

Here’s what’s coming up this fall:

A Heartfelt Farewell to a Legend
The city is bracing for a deeply emotional moment as beloved matriarch Monica Quartermaine (Leslie Charleson) is laid to rest.

Her departure marks the end of an era, touching everyone who’s ever walked through the Quartermaine living room. Fans can expect tearful scenes and a reunion of family and friends that underscore just how central Monica has been to Port Charles’ legacy.

A Wild Card Called Drew
General Hospital teases a bombshell return this fall from none other than Drew Cain (Cameron Mathison), whose storyline has kept viewers glued to their screens. After a long run as an unsettling antagonist, his reappearance promises to shake the foundations of multiple relationships—and possibly rekindle old wounds. Many fans are speculating whether this is the long-awaited character exit they’ve been waiting for.

A Daytime Legend Joins the Cast
Drama gets a serious boost with daytime icon Erika Slezak joining General Hospital this fall. Best known as Victoria Lord on One Life to Live, the multi–Emmy-winning actress brings serious gravitas to the canvas. Details on her character remain under wraps, but her mere arrival signals a major shift in Port Charles’ power dynamics.

Why This Autumn Will Be Unforgettable
This is one of those rare seasons where the past and future collide head-on. Monica’s farewell, combined with Drew’s possible return, confront Port Charles with echoes of its legacy—and its darkest regrets. And with Erika Slezak stepping into the fray, expect intrigue, alliances, and secrets to surface in ways that only a daytime legend can deliver.