In the upcoming General Hospital episode previewed for September 29, Anna Devane finds herself at the epicenter of a seismic shift in the Drew Cain investigation — as new evidence lands in her hands and sets off a chain reaction of revelations around Port Charles.

Anna’s New Lead in the Shooting Case

The drama kicks off with Anna in disbelief while on the phone — the preview shows her gaining access to fresh, shocking evidence tied to Drew Cain’s shooting.

She utters, “That is a turn of events,” signaling that whatever she’s seen challenges the status quo. This moment suggests that previously locked paths or suppressed clues may now be reopened.

In past weeks, the mystery around who shot Drew has involved a long list of suspects: Sonny, Carly, Michael, Alexis, and more. Anna’s new update may pivot the investigation toward someone unexpected or confirm suspicions others have held in secret.

Parallel Reveals & Reactions

Beyond Anna’s discovery, several other storylines move forward dramatically:

• Nina’s Shocking News: Nina convenes Liesl and Britt for what appears to be a family emergency — but it’s revealed she’s not referring to either of them. Her true revelation: Nathan West is alive, and in the hospital.

• Willow Meets Nathan: Willow Tait, finally, introduces herself to her newly awakened uncle, formally telling him: “I’m Willow Tait — your niece.” That simple moment reflects years of anguish, identity struggles, and longing.

• Alexis in Peril: Alexis Davis is placed in a dangerous position. Whether the threat is physical, legal, or emotional remains unclear, but the preview signals she must act quickly to protect herself.

• Tracy & Veronica Encounter: In the family crypt, Tracy confronts Veronica Bard — the mysterious figure played by Erika Slezak — demanding explanations. That encounter is sure to stir more secrets than answers.

What It All Means

This episode looks to be a turning point. Anna’s fresh evidence may unlock or derail the ongoing investigation, placing new pressure on suspects and shifting alliances. The confirmation of Nathan’s survival threatens to turn family relationships upside down. Meanwhile, Alexis’s danger and Tracy’s confrontation cut at personal stakes, reminding viewers that the fallout is more than procedural — it’s deeply personal.

Far from being isolated plot threads, these revelations are interconnected. Anna’s evidence, Nina’s news, and Tracy’s anger could all converge around the same set of secrets that many in Port Charles have been racing to hide.

By the end of the episode, characters may no longer be able to separate what’s true from what they believed. Port Charles will feel the tremors of truth — and few will be left unscathed.