As fall descends on Port Charles, General Hospital promises one of its most electrifying seasons yet.

Co-head writers Elizabeth Korte and Chris Van Etten tease a storyline brimming with loss, shocking comebacks, and emotional drama — weaving a tapestry that will ignite Port Charles like never before.

A Farewell to Remember
One of the most poignant events of the season is the passing of monolith, Monica Quartermaine (Leslie Charleson).

Her death is more than a storyline—it’s a cultural moment for the show and a deeply emotional milestone for long-time viewers. Jason and Tracy lead a mourning process that brings the Quartermaines — and Port Charles itself — together… though, as always, tensions simmer beneath the surface.

A New Power Moves In
In the wake of Monica’s departure, Port Charles welcomes daytime legend Erika Slezak (of One Life to Live fame). Her character arrives with mysterious links to the Quartermaine family — and unexpected strings that could shift the balance of power across town.

Drew Cain’s Dangerous Spiral
Once an underdog in the Quartermaine world, Drew Cain (Cameron Mathison) has dug himself a deep hole with schemes and betrayals. Now a target of his own making, Drew’s enemies are closing in, and his fate this fall hangs by a thread.

Miracles… or Omens?
Perhaps the most gripping twist is the dual returns of Britt Westbourne (Kelly Thiebaud) and Nathan West (Ryan Paevey). Their reappearances feel less like reunions and more like omens — and in Anna Devane’s eyes, there’s only one person who could be pulling the strings: Cesar Faison.

Cassadine Collateral
Adding further ignition to the season is the return of Valentin Cassadine (James Patrick Stuart) — still dealing with WSB custody — and his daughter Charlotte (Scarlett Fernandez). Valentin may have an unlikely alliance to negotiate while Charlotte wields her influence in dangerous ways.

Sonny Under Siege
Sonny Corinthos is facing a new kind of war. Jenz Sidwell has weaponized politics—not violence—to try and topple him. Add ADA Justine Turner to the mix, and Sonny’s legal and political maneuvering may become his greatest test yet.

Web of Romance and Deception
Elsewhere, relationships unravel and alliances tear. Portia, Curtis, Jordan, and Isaiah are caught in a moral and emotional battle that may permanently alter their paths. Meanwhile, Britt’s return pulls in multiple families, challenging trust at every turn—especially for Jason.