The new season of General Hospital is preparing to flip Port Charles upside down.

From heartbreaking farewells to stunning returns, this fall brings the kind of emotional intensity and shock value that longtime fans live for.

The End of an Era
Monica Quartermaine (Leslie Charleson), one of the longest-running pillars of the show, is being laid to rest.

Her farewell is not just a moment for her family but a cultural milestone for the series. Into this emotional gap steps Erika Slezak, who joins the cast as a mysterious newcomer with deep potential to disrupt the town’s fragile balance.

Drew Cain’s Downfall
For Drew (Cameron Mathison), ambition comes at a steep price. His attempt to climb higher in the Quartermaine world has led him down a dangerous path. Once the underdog fighting for a seat at the table, he is now facing the fallout of his own darker impulses. The big question is whether Drew can salvage his soul — or if he has already crossed the point of no return.

Back From the Dead?
Few things shock Port Charles like a resurrection. Fans will see Nathan West (Ryan Paevey) and Britt Westbourne (Kelly Thiebaud) back in the mix, sparking disbelief and suspicion. Their reappearances don’t just shake the characters they loved and left — they also reopen old wounds tied to Faison’s legacy.

Meanwhile, Valentin Cassadine (James Patrick Stuart) escapes WSB custody, and his reunion with daughter Charlotte (Scarlett Fernandez) adds another layer of unpredictability. Charlotte’s loyalties may be tested in ways that could pit her against people she loves most.

Sonny Under Siege
Sonny Corinthos faces one of his trickiest seasons yet. While he’s no stranger to enemies, Jenz Sidwell plays the game differently — using political leverage and psychological warfare. ADA Justine Turner’s involvement raises the stakes, putting Sonny in a position where one wrong move could cost him everything.

Family Drama Everywhere
Romantic entanglements and family tensions intensify. Carly is pulled into dangerous secrets. Josslyn’s decisions put her relationships at risk. Portia and Curtis may not survive their marital struggles. At the same time, the younger generation is being primed for bigger storylines, ensuring that the future of Port Charles is as chaotic as its present.