Port Charles is on the brink as General Hospital rolls into fall 2025.

And the upcoming months promise heartbreak, suspense, and unexpected alliances.

Co-head writers Elizabeth Korte and Chris Van Etten tease a story arc packed with emotional hurdles and shocking twists.

All underscored by the show’s signature blend of love, family, and deception.

A Farewell to a Port Charles Legend
The season opens with the untimely passing of Monica Quartermaine (Leslie Charleson), a beloved matriarch and soap opera icon. Her death isn’t merely another plot point — it’s a cultural milestone, sending ripples of grief through the Quartermaine family and the entire town. It also creates a void just as daytime legend Erika Slezak arrives in Port Charles. Her mysterious new character carries ties to the Quartermaines and may shift the power dynamics across the canvas.

Drew Cain’s Dangerous Descent
Once an underdog, Drew Cain (Cameron Mathison) has transformed into a divisive force. Ostracized by the Quartermaines and struggling with resentment, Drew’s bold moves have earned him numerous enemies. As the season unfolds, his fate teeters between redemption and ruin.

Unbelievable Returns
In a dramatic twist, two presumed-dead characters make miraculous comebacks: Nathan West (Ryan Paevey) and Britt Westbourne (Kelly Thiebaud). Their return shocks everyone, especially Anna Devane, who suspects Cesar Faison is behind their survival. Meanwhile, they open old wounds and stir chaos across family lines.

Adding to the upheaval is the return of Valentin Cassadine (James Patrick Stuart) and his daughter Charlotte (Scarlett Fernandez). Valentin is actively seeking freedom from WSB custody, while Charlotte’s connection to her father could be a powerful game-changer.

Sonny’s High-Stakes Chess Match
Sonny Corinthos is under fire—from internal family drama to external threats. Jenz Sidwell is waging a political war, not a mob war, and ADA Justine Turner adds another layer of legal danger. It’s a season where Sonny’s survival depends on strategy, not violence.

Love’s Falter and Forbidden Bonds
Romances and rivalries are fraying. Britt, back in town, is bound to split opinions and test bonds. Carly might discover her husband Brennan’s role in their daughter Josslyn’s undercover work, putting their marriage to the test—after all, “men who cross Carly pay the price.” Complex dynamics swirl around Portia, Curtis, Jordan, and Isaiah, each facing their own trials in a town where secrets are deadly.