Port Charles is no stranger to turmoil, but the week of September 15 takes drama to a new level.

Spoilers confirm that Anna Devane and Britt Westbourne dominate the spotlight, each on a collision course with destiny.

Anna’s story begins with a discovery.

While chasing leads on Drew Cain’s shooting, she uncovers fresh evidence that could reshape everything investigators—and fans—thought they knew.

Is Michael closer to being exposed? Could Willow’s name surface as a surprise suspect? Whatever Anna has found, it places her directly in the crosshairs of a dangerous game. She knows that the truth is a double-edged sword: vital to justice, but devastating to those unprepared for it.

Meanwhile, Britt Westbourne steps back into Port Charles, sparking one of the most anticipated confrontations in recent memory. Her reunion with Liesl Obrecht is anything but warm. Their heated clash dredges up years of lies and emotional scars, creating a storm of accusations and heartbreak. Liesl, who fought to control Britt’s narrative, suddenly faces the fury of a daughter who refuses to remain silent. The fallout will ripple far beyond their family drama, threatening to unravel alliances across town.

Carly, Nina, and the Quartermaine circle also feel the tension. Carly leans into her protective instincts, bracing for the storm Anna’s evidence may unleash. Nina, caught between alliances, may have to choose sides she never wanted to pick. And for Michael, who has been under suspicion for weeks, the tightening noose could finally close in.

As the week progresses, it becomes clear that Port Charles is heading for a reckoning. Britt’s explosive return forces people to confront painful truths, while Anna’s discovery brings the investigation closer to its breaking point. Together, these stories remind viewers of what makes General Hospital unmissable: the high stakes of family, love, betrayal, and survival.